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Title

Towards a Computational Formalization for Foundations of Medicine
Author

Stephen Wolfram
Organization: Wolfram Research, Inc.
URL: http://www.stephenwolfram.com
Book information

Publisher: Wolfram Media
Copyright year: 2025
ISBN: 9781579551087
Buy this book
Contents

  • A Theory of Medicine?
  • A Minimal Metamodel
  • The Diversity and Classification of Disease
  • Diagnosis & Prognosis
  • The Problem of Finding Treatments
  • The Effect of Genetic Diversity
  • Biological Evolution and Our Model Organism
  • What It Means and Where to Go from Here
  • Thanks & Notes
Description

A Metamodel for the Foundations of Medicine

What would a general theory of medicine look like? Stephen Wolfram proposes one grounded in computation. By evolving simple programs as model organisms, he shows how perturbations can stand in for disease and how counter-perturbations can mimic treatment, with genetic diversity reflected in variant rules. The results mirror core challenges of medical science: the wide range of outcomes, the difficulty of prognosis and the uneven success of treatments. The essay positions medicine alongside physics and evolution as a domain whose essential features can be captured in abstract computational form.

This is not applied biomedicine but a research agenda: an invitation to study medicine's foundations with computation as the guiding principle. It points toward a future in which algorithmic models deepen our intuition for health, disease and healing.
Subject

*Science > Biology
Keywords

biology and computation, computational medicine, modeling health and disease, automated medical diagnosis treatment computation, model health care disease foundations medicine, biology abstract future symptoms science, modeling approach framework theory