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The Latent Class Twin Method
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| Organization: | National Cancer Institute |
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The latent class twin method assumes two types of latent classes: an environmental susceptibility (ES) latent class and a genetic susceptibility (GS) latent class. The GS latent class represents a genetic contribution associated with high probabilities of independent outcomes. The ES latent class involves background probabilities of dependent outcomes. The latent class twin method estimates the genetic prevalence, which is the fraction of persons in the genetic susceptibility latent class, and the heritability fraction, which is the fraction of persons in the genetic susceptibility latent class with the trait or outcome.
Reference: Baker SG. The latent class twin method. Biometrics 2016; 72: 827-834.
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Twin method, latent class
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| The Latent Class Twin Method (22.2 KB) - Unknown MIME type |
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