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Time- and Loading-Dependence in the McKone Model for Dermal Uptake of Organic Chemicals from a Soil Matrix

D. E. Burmaster
N. Maxwell
Journal / Anthology

Risk Analysis
Year: 1991
Volume: 11
Issue: 3
Page range: 491-497

McKone has recently proposed an innovative two-layer model for dermal uptake of organic chemicals from a soil matrix that explicitly includes variables for properties of the chemical, the soil, the skin, and the exposure. In this note, we investigate the joint time- and loading-dependencies implicit in the model by using Mathematica to find and plot a closed-form function for the uptake fraction for six aromatic hydrocarbons.

*Science > Chemistry
*Science > Geology and Geophysics