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Using Mathematics to Understand HIV Immune Dynamics

D. Kirschner
Journal / Anthology

Notices of the AMS
Year: 1996
Volume: 43
Issue: 2
Page range: 191-202

Since the early 1980s there has been a tremendous effort made in the mathematical modeling of the human immunodeficiency virus (HIV), the virus which causes AIDS (Acquired Immune Deficiency Syndrome). The approaches in this endeavor have been twofold; they can be separated into the epidemiology of AIDS as a disease and the immunology of HIV as a pathogen (a foreign substance detrimental to the body). There has been much research in both areas; we will limit this presentation to that of the immunology of HIV, and refer the reader to some excellent references on mathematical modeling of the epidemiology of AIDS (1,2,3,4). Our goal then is to better understand the interaction of HIV and the human immune system for the purpose of testing treatment strategies.

*Science > Biology
*Science > Medicine