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The Mathematica notebook interface, used by an overwhelming majority of users, has been an easy-to-use, but powerful environment for scientific computation, visualization, and documentation. However, despite all its many features, there are application areas in which it is not necessarily the best environment for interacting with Mathematica. Indeed, in some circumstances the standard web browser is in fact preferred. In image processing applications, for example, it is convenient to have the ability to interactively select/markup regions-of-interest in an image. In general, interactive manipulation of graphics is a feature that is rapidly growing in importance and has received a tremendous amount of attention in recent times with several complementary Wolfram products suitable for creating alternative interfaces, either already available or under development. This paper presents a GUIKit-based package for interactive selection of regions-of-interest in an image. This package, designed to be used together with the Digital Image Processing application package, adds an important usability feature to the application. It permits users to select, using the mouse, any of the Mathematica 2D graphics primitives, thus marking an image region for possible measurement or modification. Several graphical alternatives to existing image processing functions have been added to illustrate how the region-of-interest selection functions can be used to simplify selected operations.
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